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  (International Nonproprietary Name) (International ic Alphabet: ) is an angiotensin II receptor antagonist used mainly for the treatment of hypertension. Irbesartan was developed by Sanofi Research (now part of sanofiaventis). It is jointly marketed by sanofiaventis and BristolMyers Squibb under the trade names Aprovel, Karvea, and Avapro. As with all angiotensin II receptor antagonist used mainly for the reduction of renal disease progression in patients with type 2 diabetes, hypertension and microalbuminuria (30 mg/24 hours) or proteinuria (900 mg/24 hours).Rossi S, inderal use for public speaking editor. Australian Medicines Handbook 2006. Adelaide: Australian Medicines Handbook 2006. Adelaide: Australian Medicines Handbook; 2006. 0975791923 Irbesartan is also available in bination formulation with a low dose thiazide diuretic, hgh therapy cost invariably hydrochlorothiazide, to achieve an additive antihypertensive effect. 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